The first indication I had that something was amiss was in September 2009 I took three anti-sickness pills and had some very strange reactions. There is a Group related to these awful side effects on Facebook called Reglan Support Group (Primperan/Metoclopramide Read the devastating effects this drug has had on people taking it. I think I will investigate more about Boron like the reviewer above. Side effects associated with alendronic acid | RxISK If you were prescribed to take 10 mg of alendronic acid, swallow one whole tablet daily. I was left on Seroxat for 15 years and wonder if it is the reason I know have Neuropathy. I had had a two year bone scan and been told that my bone density had increased, so as far as I was concerned, the drug was working and all was well in that particular area. I read its the same Acid in cleaning products! Taking alendronic acid for at least a year can halve your chances of fractures in your wrist, hip, or spine when youve entered the menopausal stage. Ive only had one tablet of the Alendronic Acid yesterday, but seem to have quite a few of the side effects so wont have another again, and am miffed to see that people have problems for weeks even after one tablet. Common Fosamax Side Effects Doctor said it was a preemptive measure as my left hip was compromised! Other symptoms include numbness of the lips which are also dry and sometimes numbness in the chin. Engineered Nanomedicine with Alendronic Acid Corona Improves - PubMed Even a couple of paracetamol would make me ill. And of course I was already taking Seroxat, albeit a very small amount. I developed teeth probs just before diagnosis so treatment sounds scary if things are made worse by AA. I was on it for 9+ years and it caused fractures in my sacrum and pelvis. Conclusions: Alendronic acid once weekly produced greater BMD increases at both hip and spine sites and greater reductions in bone turnover relative to risedronic acid once weekly. I have just taken my first one and reading this forum is really interesting. Alendronic acid | Drugs | BNF | NICE This settled after a few days and I thought no more about it. Im 54 years old and after having a Dexa scan, was told that I have Osteoporosis. The Pembrokeshire woman living in fear because of a drug - ITV News Ive only just started on the AA but since my run in with Metoclopramide Im scared to take any drugs now. I began to take as prescribed and do not have any problems until 6 days after my 4 th dose, I was awakened in the night with uncomfortable, aching wrists. My GP told me to take alendronic acid with the calcium and vit D tabs 5 or so years ago (in my mid 40s), after a DEXA scan showed I had mild osteoporosis already. cant belive my GP gave me these awful tablets . I was prescribed Alendronic Acid 70 mg by my GP a couple of months go due to fracturing my humorous after I tripped me fell. Alendronate (Oral Route) Proper Use - Mayo Clinic Had another car ride, but then it flared up again, sometimes I limped all morning. Thus, it helps increase bone density, reduce the risk of bone fractures, and treat osteoporosis. muscle cramps or spasms, a tingling sensation in your fingers or around your mouth - these can be symptoms of low calcium levels in your blood. june 2022. I have osteopenia aged 58 and my sister has osteoporosis aged 65, she was prescribed Alendronic Acid with similar side effects. The food and drug agency should be aware of this severe health risk and compensation for reconstruction of dental work and monies for pain and suffering should be compensated. Alendronic Acid 70 mg tablets, 4 Tablets - Dock Pharmacy Hey Ive been diagnosed with polymialgia rheumatica too i was prescribed predisolone vit d evacol and now AA Im not having any side effects from it yet but reading all of these comments Im worrying about wether I should take the alendronic acid Ive only taken two up to now but have had no problem with it yet It scares you a bit, Hi I have just been precribed alendronic acid I have not taken it yet as I have had a bad cold. The following guidelines are suggested, and are likely to be revised as further evidence is published or when a national guideline is produced. I have been taking alendronic acid and adcal D3 for several months, since starting these drugs I have developed a very dry sore mouth and tongue with much reduced flow of saliva, also I have much reduced sense of taste. Thank you. prevent cancer spreading to the bone. Hi, Ive just discovered this site. One thing concerns me! Pharmaceutical drugs are just about making money and not curing people. Are there any better options to AA which people have found?? This drug is also used to treat Paget's disease. Alendronic Acid 70 mg tablets is a tablet containing the active substance alendronic acid (commonly called alendronate) and belongs to a group of non-hormonal medicines called bisphosphonates. Alendronate helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions. I drank 2 cups of coffee. When I researched Fosamax/drug intolerance I found it is a reported side effect that people (usually women aged 50 70, of course) became intolerant of other drugs whilst having taken Fosamax for 2 5 years. Hi everyone.I am new to this forum.I started taking Alendronic acid for the first time yesterday.I have had a bone density scan which shows i have oesteoporosis.I am 59 years old,considered myself quite fit until last June,I have read the side effects of these tablets and what other people have put about them.I am quite scared about taking anymore.I felt fine yesterday after taking mu first . alendronic acid has destroyed my life - mail.fgcdaura.sch.ng Hi there. I went back to my GP to inform him that I couldnt take them and he readily gave me another prescription for Risedronate 35mg one a week which I am now frightened to take because the possible side effects listed are exactly the same as the AA. Alendronic Acid Has Destroyed My Life. Hello Carol,just been asked to go and see my gp for a talk about having a break from taking alendronic acid.Going next week after taking them for more than ten years.I do remember having a bone scan after three years and the results showed some improvements in my bone density. I took the tab yesterday &.the strange & heavy uneven rhythm actually woke me up last night. blurred vision, painful or red eyes - these can be signs of swelling of the eye. The pain has travelled to her shins since stopping it. This has come to light since I collapsed in the shower , after complaining of thigh bone pain for over 2 years ! My entire body jerked violently as if I was having an epileptic fit, but I was conscious throughout. She is having pain in her legs, hips and groin. Please tell your doctor if youre taking: Your doctor might recommend you take brands of alendronic acid such as Fosavance and Bentexo along with vitamin D3 (calciferol). My Mum had taken Alendronic for 10yrs after breaking her hip. Also does anyone know what element of AA gives you the aches and pains so that I know if it will be safer for me to take the Risedronate please? My advice beware. It got better in the day, but flared up at night for a few nights, then resolved. Just had to reply to your post! Alendronic acid shortage is contributing to medication errors, warn It can support your bones depending on how long you have taken medicine. treat cancer that has spread to the bone ( secondary bone cancer or bone metastases). I stopped taking alendronic acid straight away and now wake every morning in the hope that there might be some improvement in my condition. Surgeon said her bones in the hip and pelvis crumbled away like chalk and hed never seen that as severe before. I also had pain/soreness behind the eyes and a niggling headache for 48 hours. I Have been taking Alendronic Acid Tablets for 11 months now. No other cause but the medicine . My partner had videoed two of my jerking episodes for him to see and he asked if he could have copies to show colleagues for their opinions. In the meantime her teeth fell outliterally fell outwhat on earth was happening. Because of how I tend to react and my blood test results, I thought I would research the new meds first and Im now very pleased that I did. However now it is back with a vengeance! Needless to say I will never take another one and I would like to know whether anyone knows how long Alendronic Acid takes to leave the system. There are dentists and oral surgeons in the US who will not treat people if they are on this drug. Ive not taken many of the Adcal, and havent yet taken any Alendronic Acid, and to be honest Im now thinking about not talking it at all, as the possible side effects are really worrying me. As a consequence, my Dr prescribed Alendronic Acid 70mg. Alendronic acid and teeth extraction : r/askdentists - Reddit GP is arranging for a bone scan . My crown became wobbly and fell out . I take Alendronic tablets as I had breast cancer and take the tablets for continuing bone health. Since taking alendronic, I have had difficulty in running and doing all the workout I was doing. Possible Interactions with: Calcium | Complementary and Alternative Taking Prednisone now reduced to 15mg per day and apparently it has accelerated progress of cataracts! Eventually, I Started Pilates and regular walking. I called my doctor and will go in tomorrow morning, even though pain resolved. Im just another person looking for help with my bones, having been told by my doctor that there is no alternative to Alendronic Acid. Then seen a doctor over the pains in my head he asked how long Id been taking alendronic when I told him how long Id on them, he was horrified and reported straight away.They discovered I had broken Vertebrae leaning on my spinal cord.Alendronic should be band. Some people, as early as the age of 35, experiences loss of average bone density resulting in weaker bones. I have recently been prescribed AA and, after researching this drug for its possible side effects and reading your stories, I really do not want to take it! It is relevant at this point to say that my sister lives in Australia which has different prescribing criteria. I had also gone hypothyroid. It begins as minor dental problems and can escalate to permanent jaw damage. Muscle pain all the time hot sweats but put that down to menapause each time going to doctors about my symptoms only to be told the good will out way the bad Iike hell did it only at the end of july I was walking minding my own business with friends in torquay on holiday 1 day into my holiday I was crossing the road &my leg broke in front of me so I sustained a femur fracture due to AA which has been confirmed twice it was the AA that has caused this I have now come off them my sweats have stopped along with the others symptoms all stopped all off most I put down to a long menapause. Felicity I was running 2 or 3 times, each week, circuit, bodypump, combat, body pump etc, about 14 hours of workout every week. Rare and serious effects such as femur fractures and jaw problems (osteonecrosis of the jaw) have been reported. As you age, you will notice changes in your body, such as grayed hair, wrinkles, vision problems, and hearing loss. As I was searching through my kitchen drawers, it came to me. Do not take this drug if you have mild to severe kidney problems. Fillings etc are fine but anything more invasive can be really very difficult to manage it. Fast forward to 2009. Hi. 65 fatalities, 1,292 musculoskeletal disorders, 651 poisonings, 2,537 gastrointestinal disorders. Took dose 7, and on and off right hip aches, but now radiating to thigh. Its now Friday and still feeling joint pain all over my back, its lessened but it seems to have moved from my right to left side? Where do you live Jane hope you dont mind me asking. With the agreement of my GP I have now stopped taking the tablets. 74, fractured hip. Cholesterol-lowering medications -- A class of medications known as bile acid sequestrants (including cholestyramine, colestipol, and colesevelam), used to treat high cholesterol, may interfere with normal calcium absorption and increase the loss of calcium in the urine. When I initially had a bone scan they said Id have another one after three years, Ive never had another one. This is a dangerous drug. 6.3 Shelf life. Whoa, I said, I want to do this with diet and exercise. It treats osteoporosis in postmenopausal women and men at high risk of fractures. Inhibiting osteoclast function, as bisphosphonates do, lessens bone resorption. In my diary I have written that I felt lightheaded, as if I wasnt getting enough oxygen, and that my arms and head were fizzing. Participants will receive one dose of active zoledronic acid during the first month after heart or liver transplantation and weekly placebo alendronate pills or one dose of placebo zoledronic acid and weekly active alendronate pills for the first year after transplant. I wont be taking it as I feel I may be able to find a natural alternative. Im now in my 70s and am doing my best to stay out of a wheelchair. I had settled on a very low dose of Seroxat, enough to keep withdrawal at bay but not enough to have a therapeutic effect, because I didnt need one. Took AA on Sunday and the next night I was in so much pain, I couldnt move. This settled after a few days Many thanks for all your information. I have been taking A.A for about 9/10 months. Stopping and seeing if the symptoms resolve for most drugs is the best way to prove a link some problems with some drugs may take time more time than you expect but will resolve but some may also be permanent. Avoid taking it if you have esophageal or throat conditions. Hello I am 66 and like many of you am hating taking this drug, I had breast cancer 4 years ago,so am still taking Anastrosil as it was Hormone related,which in turn apparantly helped causing bone density loss, so ws then diagnosed with osteopenia Ohh my Goodness thank you so much for your post. Store below 25C. It has given me bad acid reflux. my Dr. told me she did not want me to take the Alendronic Acid because it would loosen my teeth. Alternatives to Alendronic Acid - Osteoporosis - Inspire Can you keep us posted on whether it goes down again, and if it does whether you or anyone can work out what it is about the drug is causing this to happen and what your doctor suggests when you get to talk to him. I had open heart surgery at the end of December and didnt take the alendronate for a couple of weeks and coincidentally the swelling went I thought maybe it was caused by fluid build up due to my heart condition and thats why it was better. As I sat up from the bed my head started to pound. We would be very interested in accounts of what happens when people take RxISK reports to doctors. Did your painn go away after it left your system. Has anyone has this done ? My rheumatologist prescribed AS but I dalayed taking as I had lots of dental work to be done. I thought that I had been duped, once, into taking a drug I probably didnt need for an illness I probably didnt have, a drug that damaged my health. After reading this negative press about AA, I refused to take it. The second is absolutely & completely familiar. The whole remit of Western medicine is to treat symptoms without curing, so that long term profits can be made. Lately, i have been feeling quite unwell, and after having had all sorts of health checks I have now come to the conclusion that my strange symptoms might be due to Alendronic acid. My worry at the moment is that I need a new crown in my teeth and do not know if this permitted and if I go ahead will it affect the health of my gums. I will never take drugs like yours again. Now, the only exercise I get is pottering around my house or gently along my local high street. Given ENEMA which got things moving but still having problems so was referred for COLONOSCOPY!! This prompted me to do more research into alendronic acid, but instead of looking up this generic term, I tried the brand name Fosamax. If I apply pressure on my face in front of my ear, the ear pain lessens. She told me that all of these drugs, which is just a few, would cause me to have the same side effects. H411 (50%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment . Am I the only one the suffer from these bad side effects after taking it for the first time. It took over a year to come off Seroxat using a liquid form and the withdrawal symptoms were awful. I feel very tired and my bones are much more painful now. ). Menopause in women or low testosterone levels in men, Poor nutrition such as low-intake of calcium and vitamin D, Crohns disease, celiac disease, and other inflammatory bowel conditions that affect your body in absorbing nutrients, Calcium supplements, magnesium, iron, and zinc multivitamins, Cancer medicines such as bevacizumab or thalidomide and if youre undergoing chemotherapy. My lower teeth started getting loose and getting cavities to the point where , in 2011 I had to have the last remaining 6 lower teeth pulled and dentures made. Drug treatments to protect your bones | Macmillan Cancer Support Its recommended to take it on an empty stomach first thing in the morning. As the Corona virus is ongoing we cannot go back to the GP yet, but she is convinced all the aches started after coming off of it!! check your brand of alendronic acid may contain gluten, Dear Jane The hospital talking about infusions once a year but still waiting for a appointment. From 2013 I was prescribed alendronic acid. Ive taken a covid test because these days thats what you do if you feel ill at all. Summary Commonly reported side effects of alendronate include: decreased serum calcium and decreased serum phosphate. I also have had a bone scan pre drugs so it would be interesting to find out when I can have another scan to see whether there is an improvement or at least no further loss apart from normal degeneration of bone. Many thanks, Diagnosed with myasthenia gravis in January and prescribed boat load of tablets. After trying a variety of non-drug treatments, I went to the doctor in December 1996 with intermittent insomnia and PMS, and asked for some sleeping tablets. I am not hoi going to take anymore Alendronic acid tablets. Firstly, the potential gastric problems, secondly osteonecrosis of the jaw, and thirdly the suggestion that the quality of the bone created by the drug is not as good as normal bone. And yes side effects are happening, muscles ache, jaw aches, I did have an X-ray on my jaw and its fine TG. I also went willingly and happily to the gym twice a week and did weekly pilates. Anyhow, if anyone knows what whip lash feels like, this is worse. There are 8,218 reported reactions, bear in mind many dont report the side effects to the Yellow Card Scheme. 25 yrs later Ive had a Dexa scan and was told my spine was crumbling and the reading was far worse than the worst possible. I was diagnosed with Preliminary Billiary Cholongistis (PBC) in 2021 and am now informed I have osteopenia (May 2022); informed today that a prescription has been left at my chemist for Alendronic Acid to be taken once a week. Alendronic acid and teeth - Osteoporosis - Inspire I was put on Amitriptyline to help nerve pain. It slows down your body from producing cells that break down your old bones, giving enough time for bone-building cells to spur the growth of new bones. It's harmful if you suddenly stop taking it without a proper assessment from your healthcare provider. My appointment is on the 23rd August 1017 and I am now very concerned. Stop taking your next dose if you experience rash or hives, swelling of your face, lips, or tongue, and trouble breathing. Methods: This was a randomised, double-masked, double-dummy multicentre international study (75 centres in 27 countries in . I felt so incredibly ill the next day. No way am I taking another drug, and particularly not this one. Hi, I am 47 years old and recently found out I have osteopenia every where and osteoprosis in on of my hips. Like a lot of people I was researching AA70 when I came across this group. This drug is only available for prescription and should be taken with caution. I will come back in a few weeks and let you guys know if I have any strange side effects. Have been taking alendronic for 14 months now because I had a fall just over 15months ago and broke both knee caps, have been taking them once a week,but I find they make me dizzy so was thinking of stooping them,is this advisable? Below are essential things that you should know before taking alendronic acid: Tell your doctor if you have any dental implants or any tooth issues before taking alendronic acid. Alendronic acid may put your pregnancy at risk. You would think that and the fact that in Canada a class action suit was brought against the manufacturers of this drug, would be enough to warrant serious alarm bells. My wrists were swollen, aching. There has to be a better way. Ive been taking Alendronic Acid and Adcal for just over four years and a couple of times felt that my lower face looked slightly strange, nobody else could really tell and it didnt happen that often. Alendronate is the drug we know as Fosamax. She sent me to a specialist for a second opinion and he said take it. if the side effects persist to contact him again Due to Covid you cannot see a GP I asked for a telephone call but was told it would be at least 2 weeks before I could get an appointment Ive decided not to take my more tablets. I started reading this because after being diagnosed with breast cancer part of my ongoing treatment is Letrozole plus Alendronic Acid. Until recently I only took my Thyroid med. My life coaching business came to nothing I am unable to work. But the following is extract is certainly familiar; From then on the amount of activity needed to bring on the symptoms became less and less, to where I am now. I have had 7 weeks off work with a fractured wrist and another week off with feeling poorly due to AA (with no pay as Im a self employed carer) and need to feel fully fit before returning to work. Hi You should be able to have a dexa scan every 5 years. Angry moment! 2019 I went to the Dentist with a broken tooth, she told me after an Xray that she could only pull the tooth out as my jaw was crumbling and she could only offer me dentures from now on.